Double dens invaginatus of molarized maxillary central incisors, premolarization of maxillary lateral incisors, multituberculism of the mandibular incisors, canines and first premolar, and sensorineural hearing loss

作者：Piranit Nik Kantaputra, Robert J. Gorlin · 发表于：Clinical Dysmorphology · 年份：1992 · DOI：10.1097/00019605-199207000-00002 · 被引用次数：25 · 研究领域：Genetic Syndromes and Imprinting、dental development and anomalies、Hedgehog Signaling Pathway Studies

Molarization and premolarization of anterior teeth have never been reported before. Double dens invaginatus is an extremely rare condition. We describe an affected female who had developmental delay and congenital progressive sensorineural hearing loss. Double dens invaginatus of molarized maxillary central incisors and premolarized maxillary lateral incisors were present. In addition, multituberculated mandibular incisors, canines, and first premolar were observed. Histologically, tooth structure was unremarkable. Family history of dental abnormalities and hearing loss was denied. Clinical and radiographic examinations were those performed when the patient was 7 and 13 years old. The basic defect is postulated to be of mesenchymal origin.