Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

作者：Teresa Palomero, Maria Luisa Sulis, Maria Soledad Cortina, Pedro José Real, Kelly Barnes, Maria Ciofani, Esther Caparrós, Jean Henold Buteau, Kristy R. Brown, Sherrie L. Perkins, Govind Bhagat, Archana M. Agarwal, Giuseppe Basso, Mireia Castillo-Martín, Satoru Nagase, Carlos Cordon‐Cardo, Ramon E. Parsons, Juan Carlos Zúñiga‐Pflücker, María Domínguez, Adolfo A. Ferrando · 发表于：Nature Medicine · 年份：2007 · DOI：10.1038/nm1636 · 被引用次数：886 · 研究领域：PI3K/AKT/mTOR signaling in cancer、Cancer-related gene regulation、Acute Myeloid Leukemia Research