Hypercapnia: Mental Changes and Extrapulmonary Complications

作者：Mauricio J. Dulfano, SADAMU ISHIKAWA · 发表于：Annals of Internal Medicine · 年份：1965 · DOI：10.7326/0003-4819-63-5-829 · 被引用次数：45 · 研究领域：Respiratory Support and Mechanisms、Neonatal Respiratory Health Research、Neuroscience of respiration and sleep

Article1 November 1965Hypercapnia: Mental Changes and Extrapulmonary ComplicationsAn Expanded Concept of the "CO2 Intoxication" SyndromeMAURICIO J. DULFANO, M.D., SADAMU ISHIKAWA, M.D.MAURICIO J. DULFANO, M.D., SADAMU ISHIKAWA, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-63-5-829 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA frequent consultation to the Lung Station in a general hospital relates to patients suspected of having "CO2intoxication or narcosis." This diagnosis is commonly entertained when some mental or behavioral changes occur acutely in patients suffering from chronic obstructive pulmonary disease, especially during acute exacerbation of respiratory failure. The full blown picture of "CO2narcosis" in these patients is well known, particularly through the work of Westlake, Simpson, and Kaye (1) and Sieker and Hickam (2). However, attempts to estimate clinically the degree of carbon dioxide retention in terms of the degree of mental disturbance in any such patient...References1. WESTLAKESIMPSONKAYE EKTM: Carbon dioxide narcosis in emphysema. Quart. J. Med. 2: 155, 1955. Google Scholar2. SIEKERHICKAM HOJB: Carbon dioxide intoxication: clinical syndrome, its etiology and management, with particular reference to the use of mechanical respirators. Medicine 35: 389, 1956. CrossrefMedlineGoogle Scholar3. SCHWARTZBRACKETTCOHEN WBNCJJ: The response of...