Scanning Tunneling Microscopy of Uncoated recA-DNA Complexes

作者：Matthias Amrein, Roland Dürr, Andrzej Stasiak, Heinz Gross, Gabriele Travaglini · 发表于：Science · 年份：1989 · DOI：10.1126/science.2928803 · 被引用次数：103 · 研究领域：Force Microscopy Techniques and Applications、Advanced Electron Microscopy Techniques and Applications、Surface and Thin Film Phenomena

Uncoated recA-DNA complexes were imaged with the scanning tunneling microscope (STM). The images, which reveal the right-handed helical structure of the complexes with subunits clearly resolved, are comparable in quality to STM images of metal-coated specimens. Possible conduction mechanisms that allow STM imaging of biological macromolecules are discussed.