Facile synthesis of water-soluble, highly fluorescent graphene quantum dots as a robust biological label for stem cells

作者：Mo Zhang, Linling Bai, Weihu Shang, Wenjing Xie, Hong Ma, Yingyi Fu, De‐Cai Fang, Hui Sun, Louzhen Fan, Mei Han, Chenmin Liu, Shihe Yang · 发表于：Journal of Materials Chemistry · 年份：2012 · DOI：10.1039/c2jm16835a · 被引用次数：759 · 研究领域：Carbon and Quantum Dots Applications、Graphene and Nanomaterials Applications、Nanocluster Synthesis and Applications

We present a facile electrochemical method for synthesizing uniform sized graphene quantum dots (GQDs) with a strong yellow emission at 14% quantum yield. This approach has enabled a large-scale production of aqueous GQD solution without the need for polymeric or surfactant stabilizers. The structure and emission mechanism of the GQDs have been studied by combining extensive characterization techniques, rigorous control experiments and theoretical calculations. We further demonstrate the distinctive advantages of such GQDs for direct and efficient stem cell labeling, opening up great opportunities for their bio-medical applications.