A colorimetric and near-infrared fluorescent probe with high sensitivity and selectivity for acid phosphatase and inhibitor screening

作者：Yongqian Xu, Benhao Li, Liangliang Xiao, Jia Ouyang, Shiguo Sun, Yi Pang · 发表于：Chemical Communications · 年份：2014 · DOI：10.1039/c3cc49254k · 被引用次数：80 · 研究领域：Molecular Sensors and Ion Detection、Advanced biosensing and bioanalysis techniques、Advanced Nanomaterials in Catalysis

A dual-channel including a colorimetric and fluorescent probe based on the aggregation-caused quenching (ACQ) and enzymolysis approach has been presented to screen acid phosphatase (ACP) and its inhibitor. Moreover, the ACP activity was determined by real time assay.