Cotransmitters in the Motor Nerves of the Guinea Pig Vas Deferens: Electrophysiological Evidence

作者：Peter Sneddon, D P Westfall, J S Fedan · 发表于：Science · 年份：1982 · DOI：10.1126/science.6291151 · 被引用次数：217 · 研究领域：Ion channel regulation and function、Neuroscience and Neuropharmacology Research、Muscle activation and electromyography studies

The contractile response of the guinea pig vas deferens to motor nerve stimulation is biphasic. The first phase is antagonized by the specific adenosine triphosphate-receptor antagonist arylazido aminoproprionyl adenosine triphosphate (ANAPP3), and the second by the alpha-receptor antagonist prazosin. The underlying electrical event, the excitatory junction potential, is also blocked by ANAPP3, but not by prazosin.