Effect of Aerobic Exercise on Blood Pressure

作者：Seamus Paul Whelton, Ashley Chin, Xue Xin, Jiang He · 发表于：Annals of Internal Medicine · 年份：2002 · DOI：10.7326/0003-4819-136-7-200204020-00006 · 被引用次数：1975 · 研究领域：Cardiovascular and exercise physiology、Physical Activity and Health、Blood Pressure and Hypertension Studies

PURPOSE: Physical activity has been associated with reduced blood pressure in observational epidemiologic studies and individual clinical trials. This meta-analysis of randomized, controlled trials was conducted to determine the effect of aerobic exercise on blood pressure. DATA SOURCES: English-language articles published before September 2001. STUDY SELECTION: 54 randomized, controlled trials (2419 participants) whose intervention and control groups differed only in aerobic exercise. DATA EXTRACTION: Using a standardized protocol and data extraction form, three of the investigators independently abstracted data on study design, sample size, participant characteristics, type of intervention, follow-up duration, and treatment outcomes. DATA SYNTHESIS: In a random-effects model, data from each trial were pooled and weighted by the inverse of the total variance. Aerobic exercise was associated with a significant reduction in mean systolic and diastolic blood pressure (-3.84 mm Hg [95% CI, -4.97 to -2.72 mm Hg] and -2.58 mm Hg [CI, -3.35 to -1.81 mm Hg], respectively). A reduction in blood pressure was associated with aerobic exercise in hypertensive participants and normotensive participants and in overweight participants and normal-weight participants. CONCLUSIONS: Aerobic exercise reduces blood pressure in both hypertensive and normotensive persons. An increase in aerobic physical activity should be considered an important component of lifestyle modification for prevention an...