Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis

作者：Colin N A Palmer, Alan David Irvine, Ana Terron-Kwiatkowski, Yiwei Zhao, Haihui Liao, Simon P. Lee, David R. Goudie, Aileen Sandilands, Linda Campbell, Frances J.D. Smith, Gráinne M. O’Regan, Rosemarie M. Watson, Joanne Elizabeth Cecil, Sherri J. Bale, John G. Compton, John J DiGiovanna, Philip H. Fleckman, Sue Lewis‐Jones, Gehan Arseculeratne, Ann Sergeant, Colin S. Munro, Brahim El Houate, Ken McElreavey, Liselotte Brydensholt Halkjær, Hans Bisgaard, Somnath Mukhopadhyay, W.H. Irwin McLean · 发表于：Nature Genetics · 年份：2006 · DOI：10.1038/ng1767 · 被引用次数：2989 · 研究领域：Dermatology and Skin Diseases、Allergic Rhinitis and Sensitization、Food Allergy and Anaphylaxis Research