Towards Artificial Ion Channels: Transport of Alkali Metal Ions across Liposomal Membranes by “Bouquet” Molecules

作者：Marko J. Pregel, Ludovic Jullien, Jean‐Maríe Lehn · 发表于：Angewandte Chemie International Edition in English · 年份：1992 · DOI：10.1002/anie.199216371 · 被引用次数：132 · 研究领域：Molecular Sensors and Ion Detection、Electrochemical Analysis and Applications、Lipid Membrane Structure and Behavior

If “bouquet” molecules with a central crown ether or cyclodextrin unit and poly(oxyethylene) or polymethylene arms are built into the membranes of liposomes (as shown in the diagram), Na+ and Li+ ions can be transported across the membrane. All the results are consistent with a channel transport mechanism.