Epidemiology and typing of Clostridium difficile

作者：P. Jumaa, Brendan W. Wren, Soad Tabaqchali · 发表于：European Journal of Gastroenterology & Hepatology · 年份：1996 · DOI：10.1097/00042737-199611000-00002 · 被引用次数：8 · 研究领域：Clostridium difficile and Clostridium perfringens research、Antimicrobial Resistance in Staphylococcus、Nosocomial Infections in ICU

Clostridium difficile is now established as the most common nosocomial enteric pathogen causing pseudomembranous colitis, antibiotic-associated colitis and antibiotic-associated diarrhoea. Antibiotic therapy is the most important risk factor in colonization and infection with C. difficile. However, other factors are involved such as age and underlying illness. The introduction of reliable typing and fingerprinting methods has demonstrated hospital acquisition and cross-infection with C. difficile and has been important in improving our understanding of the epidemiology and pathogenicity of C. difficile.