Failure of Parenteral Vaccines to Protect Monkeys Against Experimental Shigellosis

作者：S. B. Formal, Ronald M. Maenza, S. Austin, E. H. LaBrec · 发表于：Experimental Biology and Medicine · 年份：1967 · DOI：10.3181/00379727-125-32087 · 被引用次数：61 · 研究领域：Escherichia coli research studies、Viral gastroenteritis research and epidemiology、Immunotherapy and Immune Responses

Monkeys injected subcutane-ously with either a combination of heat-killed or acetone-killed S. flexneri 2a vaccines or with vaccines made from living, virulent S. flexneri are not rendered resistant to experimental oral challenge with the homologous organism.