Endothelium-Dependent Contractions in Arteries and Veins

作者：Paul M. Vanhoutte · 发表于：Blood Vessels · 年份：2008 · DOI：10.1159/000158688 · 被引用次数：76 · 研究领域：Nitric Oxide and Endothelin Effects、Eicosanoids and Hypertension Pharmacology、Mitochondrial Function and Pathology

Endothelium-dependent contractions of isolated veins can be induced with arachidonic acid and thrombin. Anoxia causes endothelium-dependent contractions in a variety of isolated arteries and veins. Rapid stretch and acetylcholine contract cerebral arteries with, but not those without endothelium. Acetylcholine (and serotonin) cause endothelium-dependent contractions in the aorta of the spontaneously hypertensive, but not that of the normotensive rat.