Psychomotor slowing and subcortical-type dysfunction in depression.

作者：Robert P. Hart, J. Kwentus · 发表于：Journal of Neurology Neurosurgery & Psychiatry · 年份：1987 · DOI：10.1136/jnnp.50.10.1263 · 被引用次数：94 · 研究领域：Functional Brain Connectivity Studies、Cognitive Abilities and Testing、Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Elderly patients with major depression and normal controls completed the Sternberg short-term memory scanning procedure and WAIS Digit Symbol. Depressed patients demonstrated psychomotor slowing on both tasks, but normal response latency as a function of memory set size on the Sternberg procedure. While cognitive-behavioural slowing may be observed in both depressive illness and subcortical neurological disorders, a normal rate of processing information centrally appears to distinguish depression from certain of these disorders. Psychomotor slowing in the presence of normal information processing speed might be explained by a deficit in motivational state associated with depression.