Strategies for dielectrophoretic separation in laboratory-on-a-chip systems

作者：Michael Hughes · 发表于：Electrophoresis · 年份：2002 · DOI：10.1002/1522-2683(200208)23:16<2569::aid-elps2569>3.0.co;2-m · 被引用次数：401 · 研究领域：Microfluidic and Bio-sensing Technologies、Electrostatics and Colloid Interactions、Microwave and Dielectric Measurement Techniques

Dielectrophoresis--the induced motion of polarizable particles in nonuniform fields--has proven to be an effective method for the separation of bioparticles such as cells, viruses and proteins. In this paper, the application of dielectrophoresis in miniaturized laboratories-on-a-chip is discussed, and strategies are described for using dielectrophoresis both for the binary separation of bioparticles and for the fractionation of many populations in such devices.