Structures of Withaperuvin B and C, Withanolides of Physalis peruviana Roots

作者：Anil B. Ray, Mahendra Sahai, Partha Neogi, Yoshiteru Oshima, Hiroshi Hikino · 发表于：Heterocycles · 年份：1982 · DOI：10.3987/r-1982-01-0037 · 被引用次数：20 · 研究领域：Phytochemicals and Medicinal Plants

Two minor withanolides, withaperuvin B and C, have been isolated from the roots of Physalis peruviana.Their structures have been elucidated as those represented by formulae 1 and 2, respectively, based on chemical and spectral evidence.In a previous publication,2 the structure of withaperuvin, the major steroid of the roots of Physalis peruviana Limn6 (Solanaceae), was settled as 3 on the basis of spectral evidence and X-ray analysis of the derived androstane derivative (4).The present cooolunication describes the structure determination of withaperuvin 8 and C, the two minor steroidal constituents ieolated from the same plant source.Withaperuvin B, m,p.269-270•‹, [alD + 2 1 5 * (pyridine), w a s Found to possess molecular weight 502 (FD-MS) which,