Studies leading to the identification of ZD1839 (iressa™): an orally active, selective epidermal growth factor receptor tyrosine kinase inhibitor targeted to the treatment of cancer

作者：Andrew J Barker, Keith H. Gibson, Walter Grundy, Andrew A. Godfrey, Jeffrey J. Barlow, Mark P. Healy, James R. Woodburn, Susan E. Ashton, Brenda J Curry, Lynn Scarlett, Lianne Henthorn, Laura M. Richards · 发表于：Bioorganic & Medicinal Chemistry Letters · 年份：2001 · DOI：10.1016/s0960-894x(01)00344-4 · 被引用次数：570 · 研究领域：HER2/EGFR in Cancer Research、Quinazolinone synthesis and applications、Synthesis and biological activity