Epithelial-mesenchymal signalling regulating tooth morphogenesis

作者：Irma Thesleff · 发表于：Journal of Cell Science · 年份：2003 · DOI：10.1242/jcs.00410 · 被引用次数：747 · 研究领域：dental development and anomalies、Oral and Maxillofacial Pathology、Cancer-related gene regulation

Teeth develop as ectodermal appendages in vertebrate embryos, and their early development resembles morphologically as well as molecularly other organs such as hairs and glands. Interactions between the ectoderm and underlying mesenchyme constitute a central mechanism regulating the morphogenesis of