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Regional localization of three probes closely linked to the cystic fibrosis locus by deletion analysis

作者:Brandon J. Wainwright, Peter James Scambler, R. Williamson · 发表于:Cytogenetics and Cell Genetics · 年份:2008 · DOI:10.1159/000132352 · 被引用次数:9 · 研究领域:Cystic Fibrosis Research Advances、Congenital Ear and Nasal Anomalies、Genomic variations and chromosomal abnormalities

A cell line hemizygous for a deletion of the human chromosome region 7q22----q32 was used for fine mapping three probes closely linked to the cystic fibrosis locus. The three markers, J.3.11, 7c22, and met, were all found to be deleted from the region 7q22----q32. This finding, in combination with previously published mapping data, led to the assignment of J3.11 to 7q22.