An Engineered Spider Silk Protein Forms Microspheres

作者：Ute K. Slotta, Sebastian Rammensee, Stanislav N. Gorb, Thomas Scheibel · 发表于：Angewandte Chemie International Edition · 年份：2008 · DOI：10.1002/anie.200800683 · 被引用次数：172 · 研究领域：Silk-based biomaterials and applications、Surface Modification and Superhydrophobicity、Adhesion, Friction, and Surface Interactions

Fibrils or spheres? Spider silk proteins belong to the class of natively unfolded proteins. Depending on the experimental conditions, these proteins form nanofibrils or microspheres following two distinct aggregation pathways. A detailed model describes the assembly mechanism of spider silk proteins into microspheres.