Is HPV-18 present in human breast cancer cell lines?

作者：Ivana Peran, Anna T. Riegel, Yuhai Dai, Richard Schlegel, Xiaoqiang Liu · 发表于：British Journal of Cancer · 年份：2010 · DOI：10.1038/sj.bjc.6605671 · 被引用次数：6 · 研究领域：Cervical Cancer and HPV Research、Molecular Biology Techniques and Applications、Cancer-related Molecular Pathways

Although several studies have suggested an association between breast cancer and human papillomavirus (HPV) infection ( de Villiers et al, 2005 ; Cazzaniga et al, 2009 ), two recent papers published in the British Journal of Cancer ( Heng et al, 2009 ; Lawson et al, 2009 ) were particularly provocative. The authors claimed that both primary human breast cancers and two well-characterised breast cancer cell lines (MDA-MB-175VII and SK-Br-3) contained HPV-18, a type of HPV found with increased frequency in adenocarcinomas ( Iwasawa et al, 1996 ; Burk et al, 2003 ).