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Wall Teichoic Acid-Dependent Adsorption of Staphylococcal Siphovirus and Myovirus

作者:Guoqing Xia, Rebecca M. Corrigan, Volker Winstel, Christiane Goerke, Angelika Gründling, Andreas Peschel · 发表于:Journal of Bacteriology · 年份:2011 · DOI:10.1128/jb.01412-10 · 被引用次数:169 · 研究领域:Bacteriophages and microbial interactions、Viral Infections and Immunology Research、Antimicrobial Resistance in Staphylococcus

The molecular interactions between staphylococcal phages and host cell surfaces are poorly understood. Employing Staphylococcus aureus teichoic acid mutants, we demonstrate that wall teichoic acid (WTA), but not lipoteichoic acid, serves as a receptor for staphylococcal siphovirus and myovirus, while only the siphovirus requires glycosylated WTA.