Disulfide cross-linked cholic-acid modified PEG–poly(amino acid) block copolymer micelles for controlled drug delivery of doxorubicin

作者：Yuling Li, Yuling Shen, Sai Wang, Dandan Zhu, Baixiang Du, Jihong Jiang · 发表于：RSC Advances · 年份：2015 · DOI：10.1039/c5ra02553b · 被引用次数：22 · 研究领域：Lanthanide and Transition Metal Complexes、Supramolecular Chemistry and Complexes、Nanoparticle-Based Drug Delivery

Reduction responsive biodegradable core-cross-linked micelles are developed form lipoic acid and cholic acid decorated poly(ethylene glycol)- b -poly( l -glutamic acid) block copolymers and investigated for intracellular doxorubicin release.