Acellular Synthesis of a Human Enamel‐like Microstructure

作者：Houshou Chen, Zhiyong Tang, Jing Liu, Kai Sun, Syweren Chang, Martin C. Peters, John F. Mansfield, Agata Czajka-Jakubowska, Brian H. Clarkson · 发表于：Advanced Materials · 年份：2006 · DOI：10.1002/adma.200502401 · 被引用次数：202 · 研究领域：Bone Tissue Engineering Materials、Bone and Dental Protein Studies、Dental Trauma and Treatments

A mild hydrothermal process is used as a direct method to produce synthetic human enamel prism-like structures that are biocompatible with dental pulp stem cells. The rod-like fluorapatite crystals are very similar in chemical composition and in structural dimensions to natural tooth enamel (see figure).