Aneurysm Associated with Chronic Mucocutaneous Candidiasis during Long-Term Therapy with Ketoconazole

作者：Dominique Leroy, A. Dompmartin, J P Houtteville, J Théron · 发表于：Dermatologica · 年份：2009 · DOI：10.1159/000248386 · 被引用次数：15 · 研究领域：Antifungal resistance and susceptibility、Peripheral Neuropathies and Disorders、Vasculitis and related conditions

A little girl who was suffering from chronic mucocutaneous candidiasis also had a cellular immune deficiency and undetectable IgA levels. She was treated continuously for 6 years with ketoconazole at the same dosage of 200 mg/day. She was rapidly clear from infection and did not relapse although her immune abnormalities persisted. During this long-term therapy, voluminous fusiform intracranial aneurysm appeared, causing a paresis of the four limbs. Are they mycotic aneurysms?