Succinic dehydrogenase-cytochrome system of cells intracellular respiratory system catalysing aerobic oxidation of succinic acid

作者：David Keilin, Edward F. Hartree · 发表于：Proceedings of the Royal Society B Biological Sciences · 年份：1940 · DOI：10.1098/rspb.1940.0040 · 被引用次数：148 · 研究领域：Microbial Metabolic Engineering and Bioproduction、Photosynthetic Processes and Mechanisms、Enzyme Catalysis and Immobilization

Abstract Succinic dehydrogenase-cytochrome system, even in the cell-free colloidal preparation, behaves like a true respiratory system of the cell, showing the high catalytic activity and being affected by all the inhibitors in the same way and to the same degree as the respiration of intact cells. The efficiency of this system depends not only on the integrity of all its components but also on that of the colloidal structure which supports them and assures their mutual accessibility. The paper deals with the properties of each of the components of the system and with the mechanism of their interreactions.