The MIntAct project—IntAct as a common curation platform for 11 molecular interaction databases

作者：Sandra E. Orchard, Mais G. Ammari, Bruno Aranda, Lionel Breuza, Leonardo Briganti, Fiona C. Broackes-Carter, Nancy H. Campbell, Gayatri B. Chavali, Carol C. L. Chen, Noemí del‐Toro, Margaret Duesbury, Marine Dumousseau, Eugenia Galeota, Ursula G. Hinz, Marta Iannuccelli, Sruthi Jagannathan, Rafael C. Jiménez, Jyoti R. Khadake, Astrid Lagreid, Luana Licata, Ruth C. Lovering, Birgit Meldal, Anna N. Melidoni, Mila Milagros, Daniele Peluso, Livia Perfetto, Pablo Porras, Arathi Raghunath, Sylvie Ricard‐Blum, Bernd Roechert, André Stutz, Michael Tognolli, Kim Van Roey, Gianni Cesareni, Henning Hermjakob · 发表于：Nucleic Acids Research · 年份：2013 · DOI：10.1093/nar/gkt1115 · 被引用次数：1987 · 研究领域：Bioinformatics and Genomic Networks、Metabolomics and Mass Spectrometry Studies、Computational Drug Discovery Methods

IntAct (freely available at http://www.ebi.ac.uk/intact) is an open-source, open data molecular interaction database populated by data either curated from the literature or from direct data depositions. IntAct has developed a sophisticated web-based curation tool, capable of supporting both IMEx- and MIMIx-level curation. This tool is now utilized by multiple additional curation teams, all of whom annotate data directly into the IntAct database. Members of the IntAct team supply appropriate levels of training, perform quality control on entries and take responsibility for long-term data maintenance. Recently, the MINT and IntAct databases decided to merge their separate efforts to make optimal use of limited developer resources and maximize the curation output. All data manually curated by the MINT curators have been moved into the IntAct database at EMBL-EBI and are merged with the existing IntAct dataset. Both IntAct and MINT are active contributors to the IMEx consortium (http://www.imexconsortium.org).