HomeoDB2 : functional expansion of a comparative homeobox gene database for evolutionary developmental biology

作者：Ying‐Fu Zhong, Peter W. H. Holland · 发表于：Evolution & Development · 年份：2011 · DOI：10.1111/j.1525-142x.2011.00513.x · 被引用次数：128 · 研究领域：Genomics and Phylogenetic Studies、Chromosomal and Genetic Variations、CRISPR and Genetic Engineering

Homeobox gene database (HomeoDB), a manually curated database of homeobox genes and their classification, has been well received since its release in 2008. Here, we report HomeoDB2, an expansion and improvement of the original database that provides greater functionality for the user. HomeoDB2 includes all homeobox loci from 10 animal genomes (human, mouse, chicken, frog, zebrafish, amphioxus, nematode, fruitfly, beetle, honeybee) plus tools for downloading sequences, comparing between species and BLAST searching. HomeoDB2 provides a resource for studying the dynamics of homeobox gene evolution, and is freely accessible at http://homeodb.zoo.ox.ac.uk.