Comparisons of disability, quality of life, and resource use between chronic and episodic migraineurs: A clinic-based study in Taiwan

作者：Shuu‐Jiun Wang, Po-Jen Wang, Jong‐Ling Fuh, Kuan‐Po Peng, Kwong Ng · 发表于：Cephalalgia · 年份：2012 · DOI：10.1177/0333102412468668 · 被引用次数：88 · 研究领域：Migraine and Headache Studies、Traumatic Brain Injury Research、Spatial Neglect and Hemispheric Dysfunction

BACKGROUND: The International Burden of Migraine Study (IBMS) showed chronic migraine (CM) was associated with a higher disease burden than episodic migraine (EM). However, in this study Asians with CM were underrepresented. Objectives We investigated if CM and EM differed in headache-related disability, health-related quality of life (HRQoL) and health care resource utilization in Taiwan. METHODS: This study recruited patients with EM and CM from two headache clinics in Taiwan. Diagnosis was made by physicians based on Silberstein-Lipton criteria. Participants completed a questionnaire including sociodemographics, Migraine Disability Assessment (MIDAS), EuroQol five-dimensions (EQ-5D), Migraine-Specific Quality of Life v2.1 (MSQ), Patient Health Questionnaire-4 (PHQ-4), productivity and health care resource utilization. RESULTS: A total of 331 patients (EM, n = 164 (49.5%); CM, n = 167 (50.5%)) completed the study. CM patients reported a significantly higher MIDAS score, lower generic (EQ-5D visual analogue scale score and EQ-5D index score) and migraine-specific (all three domains of MSQ) HRQoL, higher levels of anxiety and depression (PHQ-4 ≥ 6) and greater health care resource utilization and productivity loss than those with EM. Positive correlations were found between these instruments and levels of anxiety and depression. CONCLUSION: Compared to EM, CM was significantly associated with higher disability, lower HRQoL and greater health care resource utilization and prod...