Hemoglobin J Taichung:beta-129 ALA--ASP.

作者：Robert Blackwell, Huihui Yang, C.-C. Wang · 发表于：PubMed · 年份：1969 · 被引用次数：22 · 研究领域：Hemoglobinopathies and Related Disorders、Hemoglobin structure and function、Iron Metabolism and Disorders

Abstract Hb J Taichung is the second singly-fast variant to be found among Chinese residents of Taiwan. The increased electrophoretic mobility of this hemoglobin results from the replacement in the β-chain of an alanyl residue by an aspartyl residue at the β-129 or βH7 position. Hb J Meinung, which was reported previously in Chinese subjects in Taiwan, has its structural aberration at β-56 or βD7 position where aspartyl replaces the glycyl residue normally found at that location. Hb J Taichung and Hb A occurred in the proportions of 41–59 in the one subject studied thus far. Although no detailed hematological study has been made, the subject appears to be normal with no obvious signs of anemia.