DNA Content and DNA-Based Centromeric Index of the 24 Human Chromosomes

作者：Mortimer L. Mendelsohn, Brian H. Mayall, E. Bogart, Dan H. Moore, Benson Perry · 发表于：Science · 年份：1973 · DOI：10.1126/science.179.4078.1126 · 被引用次数：202 · 研究领域：DNA and Nucleic Acid Chemistry、Genomic variations and chromosomal abnormalities、Chromosomal and Genetic Variations

The chromosomes of two human males were identified by fluorescent banding, restained, and measured by scanning microscopy and computer analysis. The two variables, DNA content and DNA-based centromeric index, provided almost complete discrimination of chromosome types. Some chromosomes showed significant differences in DNA content between the men, and for one man two pairs of chromosomes showed significant differences between homologs.