Vibrio cholerae hemagglutinin/lectin/protease hydrolyzes fibronectin and ovomucin: F. M. Burnet revisited

作者：Richard A. Finkelstein, Mary Boesman-Finkelstein, Peter S. Holt · 发表于：Proceedings of the National Academy of Sciences · 年份：1983 · DOI：10.1073/pnas.80.4.1092 · 被引用次数：177 · 研究领域：Escherichia coli research studies、Vibrio bacteria research studies、Endoplasmic Reticulum Stress and Disease

Cholera vibrios produce a single polymeric protein that (i) causes hemagglutination; (ii) appears to participate in their attachment to gut epithelium; (iii) may mediate their detachment from gut epithelium; and (iv) is a protease that hydrolyzes fibronectin and mucin, cleaves lactoferrin, and nicks the A subunit of the choleragen-related heat-labile enterotoxin of Escherichia coli.