NMR solution spatial structure of ‘short’ scorpion insectotoxin I5A

作者：Alexander S. Arseniev, Vladimir I. Kondakov, Vladimir N. Maiorov, Vladimir F. BYSTROV · 发表于：FEBS Letters · 年份：1984 · DOI：10.1016/0014-5793(84)80014-9 · 被引用次数：95 · 研究领域：Insect and Pesticide Research、Toxin Mechanisms and Immunotoxins、Insect-Plant Interactions and Control

Two‐dimensional 500 MHz NMR study reveals the three‐dimensional structure of the insectotoxin I5A of Buthus eupeus in aqueous solution. The most likely set of disulfide linkages is proposed. Comparison with the single crystal structure of the ‘long’ toxin v‐3 of Centruroides sculpturatus shows similarity in their α‐helical and antiparallel β‐structure fragments.