Neoplastic Characteristics of the DNA Found in the Plasma of Cancer Patients

作者：Maurice Stroun, Philippe Anker, Pierre A. Maurice, Jacqueline Lyautey, Christine Lederrey, Mirko Beljanski · 发表于：Oncology · 年份：2009 · DOI：10.1159/000226740 · 被引用次数：739 · 研究领域：Cancer Genomics and Diagnostics

About one third of patients with various malignant diseases were found to have extractable amounts of DNA in their plasma whereas no DNA could be detected in normal controls. Using the test established by one of us (M.B.), which is based on decreased strand stability of cancer cell DNA, we have found that several plasma DNA originate from cancer cells.