Long term survival in acute myeloid leukemia: The eastern cooperative oncology group (ECOG) experience

作者：John M. Bennett, Janet W. Andersen, Peter A. Cassileth · 发表于：Leukemia Research · 年份：1991 · DOI：10.1016/0145-2126(91)90124-c · 被引用次数：53 · 研究领域：Acute Myeloid Leukemia Research、Neutropenia and Cancer Infections、Lung Cancer Treatments and Mutations

A retrospective analysis of two ECOG adult AML trials conducted from 1976 to 1983 was carried out focusing on long term disease-free survival. This report summarizes the data on 545 patients with a minimum follow up of 7 1/2 years. The complete remission rate was 57% with an estimated cure rate of 12%. Of several prognostic variables examined only FAB type M3 (promyelocytic leukemia) was statistically significant (estimated cure rate of 33% vs 9% for other FAB subtypes).