High-dose chemotherapy and non-frozen autologous bone marrow transplantation in relapsed advanced lymphomas or those resistant to conventional chemotherapy

作者：Angelo Michele Carella, Gino Santini, Domenico Giordano, Francesco Frassoni, S Nati, Angela Giovanna Congiu, Domenico Occhini, Edoardo Rossi, Marina Martinengo, Eugenio E. Damasio, Giuseppe Lercari, Alberto M. Marmont · 发表于：Cancer · 年份：1984 · DOI：10.1002/1097-0142(19841215)54:12<2836::aid-cncr2820541203>3.0.co;2-r · 被引用次数：30 · 研究领域：Chemotherapy-induced cardiotoxicity and mitigation、Lymphoma Diagnosis and Treatment、Cancer Treatment and Pharmacology

Ten patients with advanced, diffuse Hodgkin's and non-Hodgkin's lymphomas responding poorly to the most widely employed primary chemotherapy regimens were treated with a high-dose chemotherapy (HDC) followed by rescue with non-frozen autologous bone marrow infusion (ABMT). Complete remission (CR) was obtained in seven of ten patients (70%) and partial remission in two. Hemopoietic recovery occurred in nine cases. These preliminary results appear to indicate that HDC and non-frozen ABMT may be successfully used in patients with resistant or relapsed lymphomas.