Mechanism of glutaredoxin—ISU [2Fe–2S] cluster exchange

作者：Wenbin Qi, J. A. Cowan · 发表于：Chemical Communications · 年份：2011 · DOI：10.1039/c0cc05079b · 被引用次数：42 · 研究领域：Metalloenzymes and iron-sulfur proteins、Metal complexes synthesis and properties、Metal-Catalyzed Oxygenation Mechanisms

Exchange of [2Fe-2S] centers between Grx2 and the cluster scaffold protein ISU, and characterization of two mutually exclusive Grx2 binding sites on ISU by isothermal titration calorimetry supports a direct link for Grx and glutathione involvement in ISU promoted Fe-S cluster biosynthesis.