Determination of nucleic acid sequence homologies and relative concentrations by a dot hybridization procedure

作者：Fotis C. Kafatos, C. Weldon Jones, Argiris Efstratiadis · 发表于：Nucleic Acids Research · 年份：1979 · DOI：10.1093/nar/7.6.1541 · 被引用次数：1396 · 研究领域：DNA and Nucleic Acid Chemistry、Advanced biosensing and bioanalysis techniques、Molecular Biology Techniques and Applications

A dot hybridization method is presented for rapidly determining the relative concentrations of nucleic acids in a mixture, as well as the extent of sequence homology between related RNA or DNA species.