Comparative in vitro activity of sanguinarine against oral microbial isolates

作者：JoAnn L. Dzink, S. S. Socransky · 发表于：Antimicrobial Agents and Chemotherapy · 年份：1985 · DOI：10.1128/aac.27.4.663 · 被引用次数：128 · 研究领域：Berberine and alkaloids research、Plant-based Medicinal Research、Synthesis and bioactivity of alkaloids

MICs of sanguinarine were determined for 52 oral reference strains and 129 fresh isolates from human dental plaque. Sanguinarine was found to completely inhibit the growth of 98% of the isolates at a concentration of 16 micrograms/ml.