HemI: A Toolkit for Illustrating Heatmaps

作者：Wankun Deng, Yongbo Wang, Zexian Liu, Han Cheng, Yu Xue · 发表于：PLoS ONE · 年份：2014 · DOI：10.1371/journal.pone.0111988 · 被引用次数：1055 · 研究领域：Bioinformatics and Genomic Networks、Gene expression and cancer classification、Microbial Metabolic Engineering and Bioproduction

Recent high-throughput techniques have generated a flood of biological data in all aspects. The transformation and visualization of multi-dimensional and numerical gene or protein expression data in a single heatmap can provide a concise but comprehensive presentation of molecular dynamics under different conditions. In this work, we developed an easy-to-use tool named HemI (Heat map Illustrator), which can visualize either gene or protein expression data in heatmaps. Additionally, the heatmaps can be recolored, rescaled or rotated in a customized manner. In addition, HemI provides multiple clustering strategies for analyzing the data. Publication-quality figures can be exported directly. We propose that HemI can be a useful toolkit for conveniently visualizing and manipulating heatmaps. The stand-alone packages of HemI were implemented in Java and can be accessed at http://hemi.biocuckoo.org/down.php.