Genes and parkinsonism.

作者：Nicholas Wood · 发表于：Journal of Neurology Neurosurgery & Psychiatry · 年份：1997 · DOI：10.1136/jnnp.62.4.305 · 被引用次数：43 · 研究领域：Metabolism and Genetic Disorders、Genetic Neurodegenerative Diseases、Mitochondrial Function and Pathology

Genes and parkinsonismParkinsonism is a common disabling condition, charac- terised clinically by akinesia, rigidity, and tremor.There is a long list of potential causes, of which the commonest is idiopathic Parkinson's disease.Its frequency increases with age and prevalence figures vary across the world.'A recent population based study estimated the age dependent prevalence at 1-4%, 2%, and 3-4% in those aged 55, 65, and 75 years or over respectively.2The clinical diagnoon