ChEBI: a database and ontology for chemical entities of biological interest

作者：Kirill N. Degtyarenko, Paula de Matos, Marcus Ennis, Janna Hastings, Magali Zbinden, Andrew Ian McNaught, Rafael Alcántara, M. Darsow, Mickaël Guedj, Michael Ashburner · 发表于：Nucleic Acids Research · 年份：2007 · DOI：10.1093/nar/gkm791 · 被引用次数：1170 · 研究领域：Biomedical Text Mining and Ontologies、Bioinformatics and Genomic Networks、Genomics and Phylogenetic Studies

Chemical Entities of Biological Interest (ChEBI) is a freely available dictionary of molecular entities focused on 'small' chemical compounds. The molecular entities in question are either natural products or synthetic products used to intervene in the processes of living organisms. Genome-encoded macromolecules (nucleic acids, proteins and peptides derived from proteins by cleavage) are not as a rule included in ChEBI. In addition to molecular entities, ChEBI contains groups (parts of molecular entities) and classes of entities. ChEBI includes an ontological classification, whereby the relationships between molecular entities or classes of entities and their parents and/or children are specified. ChEBI is available online at http://www.ebi.ac.uk/chebi/