Global prevalence and incidence of traumatic spinal cord injury

作者：Michael G. Fehlings, Anoushka Singh, Lindsay Tetreault, Sukhvinder Kalsi‐Ryan, Aria Nouri · 发表于：Clinical Epidemiology · 年份：2014 · DOI：10.2147/clep.s68889 · 被引用次数：964 · 研究领域：Spinal Cord Injury Research、Prosthetics and Rehabilitation Robotics、Traumatic Brain Injury Research

BACKGROUND: Spinal cord injury (SCI) is a traumatic event that impacts a patient's physical, psychological, and social well-being and places substantial financial burden on health care systems. To determine the true impact of SCI, this systematic review aims to summarize literature reporting on either the incidence or prevalence of SCI. METHODS: A systematic search was conducted using PubMed, MEDLINE, MEDLINE in process, EMBASE, Cochrane Controlled Trial Register, and Cochrane Database of Systematic Reviews to identify relevant literature published through June 2013. We sought studies that provided regional, provincial/state, or national data on the incidence of SCI or reported estimates of disease prevalence. The level of evidence of each study was rated using a scale that evaluated study design, methodology, sampling bias, and precision of estimates. RESULTS: The initial search yielded 5,874 articles, 48 of which met the inclusion criteria. Forty-four studies estimated the incidence of SCI and nine reported the prevalence, with five discussing both. Of the incidence studies, 14 provided figures at a regional, ten at a state or provincial level and 21 at a national level. The prevalence of SCI was highest in the United States of America (906 per million) and lowest in the Rhone-Alpes region, France (250 per million) and Helsinki, Finland (280 per million). With respect to states and provinces in North America, the crude annual incidence of SCI was highest in Alaska (83 per m...