Leg length and risk of cancer in the Boyd Orr cohort

作者：David Gunnell, George Davey Smith, J.M.P. Holly, Stephen Frankel · 发表于：BMJ · 年份：1998 · DOI：10.1136/bmj.317.7169.1350 · 被引用次数：98 · 研究领域：Birth, Development, and Health、Cancer Risks and Factors、Childhood Cancer Survivors' Quality of Life

Height is directly associated with mortality from cancer, 1 but the explanation for this association is unclear.Whereas adult height is a marker of nutrition and health throughout childhood, most growth before puberty is due to increases in leg length.Leg length can therefore be used as a marker for exposures that generate the association between adult height and cancer. 1 2 We examined the association between prepubertal leg length and mortality from cancer in the Boyd Orr cohort. 2 3