Nuclear magnetic resonance spectroscopy. Carbon-13 spectra of aliphatic carboxylic acids and carboxylate anions

作者：Robert Hagen, John D. Roberts · 发表于：Journal of the American Chemical Society · 年份：1969 · DOI：10.1021/ja01044a032 · 被引用次数：150 · 研究领域：NMR spectroscopy and applications、Molecular spectroscopy and chirality、Analytical Chemistry and Chromatography

The ^(13)C chemical shifts of each of the carbons of the simple aliphatic carboxylic acids and their corresponding anions from formic to valeric acid have been measured in aqueous solution. Perhaps surprisingly, ionization of an aliphatic acid results in a downfield shift of its carbon resonances. The results have been correlated with other substituent effects, with ^(13)C and H resonances in corresponding hydrocarbons, and with the distance between \nthe carboxylic(ate) group and the carbons undergoing resonance absorption.