Clinical patch test data evaluated by multivariate analysis

作者：J Christophersen, Torkil Menné, Per Tanghøj, Knud Erik Andersen, F Brandrup, Knud Kaaber, POUL ERIK OSMUNDSEN, Kristian Thestrup‐Pedersen, Niels K. Veien, Danish Contact Dermatitis Group · 发表于：Contact Dermatitis · 年份：1989 · DOI：10.1111/j.1600-0536.1989.tb04746.x · 被引用次数：114 · 研究领域：Contact Dermatitis and Allergies、Allergic Rhinitis and Sensitization、Occupational exposure and asthma

The aim of the present study was to evaluate the influence of individual explanatory factors, such as sex, age, atopy, test time and presence of diseased skin, on clinical patch test results, by application of multivariate statistical analysis. The study population was 2166 consecutive patients patch tested with the standard series of the International Contact Dermatitis Research Group (ICDRG) by members of the Danish Contact Dermatitis Group (DCDG) over a period of 6 months. For the 8 test allergens most often found positive (nickel, fragrance-mix, cobalt, chromate, balsam of Peru, carba-mix, colophony, and formaldehyde), one or more individual factors were of significance for the risk of being sensitized, except for chromate and formaldehyde. It is concluded that patch test results can be compared only after stratification of the material or by multivariate analysis.