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A Genetic Linkage Map of the Mouse: Current Applications and Future Prospects

作者:Neal G. Copeland, Nancy A. Jenkins, Debra J. Gilbert, Janan T. Eppig, Lois J. Maltais, Joyce C. Miller, William F. Dietrich, Alix Weaver, Stephen E. Lincoln, Robert G. Steen, Lincoln Stein, Joseph H. Nadeau, Eric S. Lander · 发表于:Science · 年份:1993 · DOI:10.1126/science.8211130 · 被引用次数:545 · 研究领域:Animal Genetics and Reproduction、Genetic Mapping and Diversity in Plants and Animals、Genomics and Chromatin Dynamics

Technological advances have made possible the development of high-resolution genetic linkage maps for the mouse. These maps in turn offer exciting prospects for understanding mammalian genome evolution through comparative mapping, for developing mouse models of human disease, and for identifying the function of all genes in the organism.