Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche

作者：Hayley L. Belnoue-Davis, Shazia Irshad, Mukesh Bansal, Hannah Rafferty, Tatjana Boitsova, Chiara Bardella, Emma Jaeger, Annabelle Lewis, Luke Freeman-Mills, Francesc Castro-Giner, Pedro Rodenas-Cuadrado, Sreelakshmi Mallappa, Susan K. Clark, Huw J. W. Thomas, Rosemary E. Jeffery, Richard Poulsom, Manuel Rodriguez‐Justo, Marco R. Novelli, Runjan Chetty, Andrew R. Silver, Owen James Sansom, Florian R. Greten, Lai Mun Wang, James Edward East, Ian P.M. Tomlinson, Simon John Leedham · 发表于：Nature Medicine · 年份：2014 · DOI：10.1038/nm.3750 · 被引用次数：294 · 研究领域：Genetic factors in colorectal cancer、Cancer Genomics and Diagnostics、Digestive system and related health