Synthesis of Di(6-aminouracil-5-yl)-arylmethane: A New Product of the Reaction of 6-Aminouracil with Aldehyde

作者：Lintao Wu, Xiaobi Jing, Ming Lin, Chao‐Guo Yan, Jin Yang, Hongxiang Zhu · 发表于：Synthetic Communications · 年份：2011 · DOI：10.1080/00397911.2010.532275 · 被引用次数：7 · 研究领域：Chemical Synthesis and Analysis、Click Chemistry and Applications、Synthesis and biological activity

In this article, a new result of the reaction of 6-aminouracil with aldehyde catalyzed by BF3 and aniline is established, which gives a new strategy for the synthesis of di(6-aminouracil-5-yl)-arylmethane. The simple and convenient synthetic procedure and formation of di(6-aminouracil-5-yl)-arylmethane render this method very useful in synthetic and medicimal chemistry.