Goblet Cell Increase in Rat Bronchial Epithelium after Exposure to Cigarette and Cigar Tobacco Smoke

作者：David H. Lamb, LYNNE M. REID · 发表于：BMJ · 年份：1969 · DOI：10.1136/bmj.1.5635.33 · 被引用次数：134 · 研究领域：Inhalation and Respiratory Drug Delivery、Tracheal and airway disorders

Both cigar and cigarette tobacco produce an increase in the number of goblet cells in the rat trachea and intrapulmonary airways over a six-week period. The increase in goblet cells is similar for the two types of tobacco; in both it is proportional to increase in dose and greatest in the proximal intrapulmonary airways.